AFC Winter 2015
Held at The National Institute for Medical Research, London
January 9th 2014
Scientific Programme
Session 1 (History of AFC and Offered papers)
A brief history of the Acid Fast Club
Ann Rawkins. Public Health England, Porton Down
Toll-like receptor and inflammasome mediated response in HIV-tuberculosis-associated immune reconstitution inflammatory syndrome
Rachel PJ Lai, Graeme Meintjes, Katalin A Wilkinson, Christine M Graham, Suzaan Marais, Helen Van der Plas, Armin Deffur, Charlotte Schutz, Chloe Bloom, Indira Munagala, Esperanza Anguiano, Rene Goliath, Gary Maartens, Jacques Banchereau, Damien Chaussabel, Anne O’Garra & Robert J Wilkinson. Division of Mycobacterial Research, MRC National Institute for Medical Research
Role of Rab20 during Mycobacterium tuberculosis phagosome trafficking
Laura Schnettger, Gang Pei & Maximiliano G. Gutierrez
Mycobacterial Research, MRC National Institute for Medical Research
M. tuberculosis dysregulates vitamin D metabolism
Karolina D Witt, Zhican Wang, Kashaf Junaid, Anna K Coussens, David A Jolliffe, Robert J Wilkinson, Kenneth E Thummel & Adrian R Martineau. Queen Mary University of London.
Investigating the role of hepcidin and iron metabolism in a murine model of Mycobacterium tuberculosis infection
Rachel Harrington-Kandt, Elena Stylianou, Hal Drakesmith & Helen McShane. Jenner Institute, University of Oxford
The role of nitric oxide in the production of Rpf-dependent mycobacteria
Sarah Glenn, Obolbek Turapov, Vadim Marakov, Bavesh Kana, Peter Andrew & Galina Mukamolova. Department of Infection, Immunity and Inflammation, University of Leicester
Session 2: Offered papers and Douglas Young
Primary human airway epithelial cells are early responders to tuberculosis infection
Ann-Katrin Reuschl, M Edwards, D Connell, N Siddiqui, H Lambie, S Bremang, OM Kon, R Shattock & A Lalvani. Tuberculosis Research Centre, NHLI, Imperial College London
Helminth induced CD4+FoxP3+ T cells are associated with an impaired immune response to Mycobacterium tuberculosis
Frederic Toulza, Lilian Tsang, Michael Brown & Hazel Dockrell; London School of Hygiene and Tropical Medicine
Phenotypic resistance in mycobacteria is associated with the presence of lipid bodies not age of cells
Robert Hammond, Han Xiao, Katarina Orvacova & Stephen Gillespie. School of Medicine, University of St.Andrews
Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick type C disease cellular pathway
Paul Fineran, E. Lloyd-Evans, N. A. Lack, N. Platt, L. C. Davis, A. J. Morgan, R. Tatoturi, D. Kelly, S. Clark, A. Williams, I. Williams, W. Tynan, N. Al Eisa, A. Galione, D. Ory, D. Russell, M. Brenner, E. Sim & F. M. Platt. Department of Pharmacology, University of Oxford
Molecular profiling of the tuberculin skin test reveals diverse effects of HIV-1 infection in active tuberculosis
Lucy CK Bell, Gabriele Pollara, Mellissa Pascoe, Gillian Tomlinson, Rannakoe J. Lehloenya, Richard Meldau, Paul Elkington, Robert Miller, Alan Ramsey, Benjamin Chain, Keertan Dheda & Mahdad Noursadeghi
Mill Hill and the Acid Fast Club
Douglas Young. NIMR/Crick