AFC Winter 2016
Held at the London School of Hygiene & Tropical Medicine
Friday January 8th 2016
Scientific Programme
Session 1 (Welcome, Host presentations and Offered papers)
The TB Centre at the London School of Hygiene & Tropical Medicine – who we are and what we do
Helen Fletcher & Katherine Fielding, London School of Hygiene & Tropical Medicine
Polyfunctional CD4 T-cells and in vitro mycobacterial growth inhibition detected in Mycobacterium bovis BCG-vaccinated UK infants
Steven Smith, Andrea Zelmer, Rose Blitz, Helen Fletcher & Hazel Dockrell, London School of Hygiene & Tropical Medicine
Ex vivo mycobacterial growth inhibition assays (MGIA) as a new tool for assessment of TB vaccines
Andrea Zelmer, Satria Prabowo, Rachel Tanner, Elena Stylianou, Helen McShane & Helen Fletcher, London School of Hygiene & Tropical Medicine
The C-terminal domain of protein kinase G is required for regulation of glutamate catabolism in Mycobacterium smegmatis
Nabanita Bhattacahatyya, M. Zimmerman & H. M. O’Hare, University of Leicester
Parenteral adenoviral boost enhances BCG-induced protection, but not long-term survival in a murine model of bovine TB
Phil Hogarth, Daryan A. Kaveh, M. Carmen Garcia-Pelayo, Paul R. Webb, Esen E. Wooff, Véronique S. Bachy; Animal and Plant Health Agency
A spatial model of M. tuberculosis in the lung
Ruth Bowness, Stephen Gillespie & Mark Chaplain, University of St. Andrews
Session 2 (Offered papers)
The Suburban Cure–thoughts on dose and genetic susceptibility to TB
Andrea Cooper & John E. Pearl, University of Leicester
Does using aerosol and systemic routes of immunisation avoid anti-vector immunity and boost TB vaccine responses?
Zita-Rose Manjaly Thomas, Iman Satti, Stephanie Harris, Joel Meyer, Morven Wilkie, Michael Riste, Ali Hamidi, Sharon Sheehan, Alice Minhinnick, Henry Bettinson & Helen McShane, University of Oxford
Investigating host regulatory pathways that limit immunopathology in tuberculosis
Patience T. Brace, LB Tezera, JS Friedland, TM Millar, CG Proud & PT Elkington, University of Southampton
Towards definition of an immunological basis of protection obtained by prime-boost immunisation against bovine tuberculosis
Hannah Metcalfe, Bernardo Villarreal-Ramos, Gareth J. Jones, Sabine Steinbach, W. Ivan Morrison , Tom Connelley & Martin Vordermeier, Animal and Plant Health Agency
Targeting the mycobacterial membrane using novel antimicrobial peptides for tuberculosis therapy
Jasmeet Singh Khara, SM Newton, N Krishnan, I Uhra, M Priestman, PR Langford, PLR Ee & BD Robertson, Imperial College
Circulating serum microRNAs as novel biomarkers for bovine tuberculosis
Carolina N.Correia, Nicolas C. Nalpas, Kirsten E. McLoughlin, David A. Magee, Ronan G. Shaughnessy, John A. Browne, Adam O. Whelan, H. Martin Vordermeier, Eamonn Gormley, Bernardo Villarreal-Ramos, Stephen V. Gordon & David E. MacHugh, University College Dublin
Objectively-measured coughing patterns in pulmonary tuberculosis
Richard Turner, Graham Bothamley & Surinder Birring, Homerton University Hospital NHS Foundation Trust
