Tag: 2013

  • AFC Summer 2013 meeting

    AFC Summer 2013

    Held at University College, Dublin

    July 4th-5th 2013

    Scientific Programme

    Session 1: University College Dublin Symposium and guest speakers

    Guest speaker
    Prof Patrick Brennan, Colorado State University

    Host preference across the Mycobacterium tuberculosis complex
    Stephen Gordon, University College Dublin

    Wildlife intervention strategies for control of bovine tuberculosis
    Eamonn Gormley, School of Veterinary Medicine, UCD, Dublin

    Session 2: Trinity College Dublin Symposium and guest speakers

    Invited talk: TB vaccine efficacy trials:what can we learn and what’s next?
    Helen McShane, University of Oxford

    TBC
    Joe Keane, Trinity College Dublin

    Phylogenetic lineages of tuberculosis isolates associate with specific patient demographics in New Zealand
    Ronan F O’Toole, Trinity College Dublin

    The ancient evolution of tuberculosis as a zoonosis
    David E Minnikin, University of Birmingham, Birmingham

    Session 3: Offered papers

    TBC
    David McHugh, University College Dublin

    Genetic Analyses of a Conserved Virulence Regulon in the Mycobacterium tuberculosis complex
    Claire Healey, University College Dublin

    The Synthesis and Biological Evaluation of Mycobacterial p-Hydroxybenzoic Acid Derivatives (p-HBADs)
    Eoin Sacnlan, Trinity College Dublin

    My-D88 adapter like (Mal) is required for effective macrophage responses To Mycobacterium tuberculosis
    Cliona Ni Cheallaigh, Trinity College Dublin

    Insights into the global metabolic changes in mycobacteria during nitrogen stress
    Kerstin Williams, Imperial College London

    Session 4: Offered papers

    Biofilms and antibiotic tolerance: transcriptomic profiles of Mycobacterium smegmatis biofilms
    S.A. Lethbridge, Public Health England, Porton Down, Salisbury

    Genome-wide mapping of transcription start sites defines an extensive leaderless transcriptome in Mycobacterium tuberculosis
    Teresa Cortes,National Institute for Medical Research, MRC, London

    A transposon-mutagenesis library to study mechanisms of drug resistance in Mycobacterium tuberculosis
    Joana Fonseca, University College London

    Mannan core branching of lipo(arabino)mannan is required for initiation of mycobacterial granuloma formation in vivo
    Arun K. Mishra, MRC National Institute of Medical Research, London

    Mycobacterium leprae – A genome lost in time
    Thomas A. Mendum, University of Surrey

  • AFC Winter 2013 meeting

    AFC Winter 2013

    Held at the Royal Free Hospital, London

    January 11th 2013

    Scientific Programme

    Session 1

    Human plasma miRNA and snoRNA molecules are significantly downregulated in tuberculosis-infected individuals in response to chemotherapy but HIV-1 co-infection spoils the picture
    Isobella Honeyborne, Shirin Bokari, Silvana Christou, Clare Eckold, Alexander Pym, Timothy McHugh. UCL, London

    Carbon fixation and a mixed diet for intracellular Mycobacterium tuberculosis
    Dany J V Beste, Katharina Nöh, Sebastian Niedenführ, Tom A Mendum, Nathaniel D Hawkins, Jane L Ward, Michael H Beale, Wolfgang Wiechert and Johnjoe McFadden. Faculty of Health and Medical Sciences, Department of Microbial and Cellular Sciences, University of Surrey

    Destruction of lung extracellular matrix by MMP-1 is critical in TB pathogenesis
    Basim Al shammari, Takayuki Shiomi, Liku Tezera, Brian D Robertson, Jon S Friedland, Jeanine D’Armiento and Paul Elkington. Department of Infectious Diseases and Immunity, Imperial College London

    Non-replicating Mycobacterium tuberculosis elicits a reduced pathogenicity profile and corresponding modifications to the cell wall
    Bacon J, Alderwick LJ, Allnutt JA, Gabasova E, Watson R, Hatch KA, Clark SA, Marriott A, Rayner E, Tolley H, Pearson G, Hall G, Besra GS, Wernisch L, Williams A, Marsh PD. Health Protection Agency, Porton Down, Salisbury

    Analysis of host gene induction following MVA85A
    M. Matsumiya, Z. Lang, J. Meyer, S. Harris, A. Pathan, R. Rowland, A. Minassian, H. Fletcher, H. McShane. The Jenner Institute, University of Oxford

    Session 2

    MTS2048 a small RNA with a secret
    Joanna Houghton, Olga Schubert, Douglas Young and Kristine Arnvig. Division of Mycobacterial Research, MRC National Institute for Medical Research, Mill Hill, London

    Structure of M. tuberculosis DprE1, the target of BTZ compounds
    Sarah M Batt, Talat Jabeen, Veemal Bhowruth, Peter A Lund, Luke J Alderwick, Klaus Fütterer, Gurdyal S Besra. School of Biosciences, University of Birmingham

    Discovery of the anti-tubercular specific activity of ibuprofen and other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay
    Juan David Guzman, Dimitrios Evangelopoulos, Antima Gupta, Kristian Birchall, Solomon Mwaigwisya, Simon Gibbons, Barbara Saxty, John Malkinson, Timothy D. McHugh and Sanjib Bhakta. Mycobacteria Research Laboratory, Institute of Structural and Molecular Biology, Department of Biological Sciences, Birkbeck College, London

    Selective ESAT6-dependent necrosis of phosphatidylserine externalised neutrophils
    Robert J Francis, Rachel E Butler, Graham Stewart. Department of Microbial and Cellular Sciences, Faculty of Health and Medical Sciences, University of Surrey

    Ethnic variation in inflammatory profile in tuberculosis
    Adrian R. Martineau, Anna K. Coussens, Robert J. Wilkinson, Vladyslav Nikolayevskyy, Francis A. Drobniewski, Paul T. Elkington, Graham H. Bothamley, Robert N. Davidson, Christopher J. Griffiths. Queen Mary University of London, Barts and The London School of Medicine and Dentistry, Blizard Institute, London E1 2AB, Division of Mycobacterial Research, MRC National Institute for Medical Research, London