AFC Summer 2014

60^th Anniversary meeting, Berlin

July 10-11 2014

Scientific Programme

Session 1: Berlin + Aeras Special

TB Research in Berlin Spanning 130 Years
Stefan Kaufmann, Max Planck Institute for Infection Biology

Interferons, Inflammation and Lung Injury in TB
Anca Dorhoi, MPIIB

Molecular profiling for host biomarker discovery in health and disease
Jeroen Maertzdorf, MPIIB

Individuality in disease: patient-specific and cell-specific gene expression in TB
January Weiner, MPIIB

Session 2: Offered papers

Metabolic models of mycobacteria: systems insights into pathogenesis
Johnjoe McFadden, University of Surrey

Transcriptome analysis reveals differential innate immune response of bovine macrophages to strains of the Mycobacterium tuberculosis complex
Kevin Rue-Albrecht, David A. Magee, Kevin M. Conlon, Nicolas C. Nalpas, John A. Browne, Paul A. McGettigan, Claire Healy, Kirsten E. McLoughlin, Eamonn Gormley, David E. MacHugh and Stephen V. Gordon, University College Dublin

Tetrahydrobiopterin production by macrophages is not required for protective immunity to Mycobacterium tuberculosis
Elena Stylianou, Eileen McNeill, Rachel Kandt, Keith Channon, Helen McShane, The Jenner Institute, University of Oxford

A brief history of the Acid Fast Club
Ann Rawkins, Public Health England, Porton Down

Session 3: Offered papers

Degradosome as one of the major RNA processing complexes in mycobacteria
Przemyslaw Plocinski, Maria Macios, Emilia Niemiec, Joanna Houghton, Douglas Young and Andrzej Dziembowski, Institute of Biochemistry and Biophysics Polish Academy of Sciences

NO biomarker for TB –  Expired nitric oxide and lipid body content of tubercle bacilli in sputum
Baye Gelaw, Natalie J. Garton, Gashaw Mesele,Tadye Abeje, Salie Ayalew, Pranabashis Haldar, Abraham Assefa, and Michael R Barer, Department of Medical Microbiology, CMHS, UOG, Ethiopia

Whole genome sequencing of Mycobacterium tuberculosis from sputum: a revolution in diagnostic microbiology
Amanda Claire Brown and members of the PathSeek project consortium, Oxford Gene Technology

Characterisation of host genetic factors that influence pathogen-host interplay during Mycobacterium tuberculosis infection
K. M. Kreutzfeldt, L. Mullen, C. Finan, S. J. Waddell, A. Marchant, M. J. Newportand S. M. Sacre, Brighton & Sussex Medical School, University of Sussex

The use of gene expression profiling in Mycobacterium tuberculosis as a tool to study drug efficacy and action
Dimitrios Evangelopoulos, Aidan Hanrath,Iva Treveska, Magdalena Karlikowska, Isobella Honeyborne, Sanjib Bhakta, Simon Waddel, Philip Butcherand Timothy D. McHugh, Centre for Clinical Microbiology, Royal Free Campus, University College London

Session 4: Offered papers

Development of a BCG challenge model for the testing of vaccine candidates against bovine tuberculosis
Villarreal-Ramos, B., Berg, S., Chamberlain, L., McShane, H., Hewinson, R. G., Clifford, D., Vordermeier, M., Bovine TB Group, AHVLA, Weybridge, New Haw, Surrey

Metabolite-Regulated Shutdown of Efflux Pumps is Critical for Mycobacterial Survival in Non-Permissive Growth Conditions
Obolbek Turapov, Simon J Waddell, Asel Sarybaeva, Bernard Burke, Sarah Glenn, Griselda Tudo, Gilles Labesse, Danielle I. Young, Michael YoungPeter W. Andrew, Philip D. Butcher, Martin Cohen-Gonsaud,Galina V. Mukamolova, Department of Infection, Immunity and Inflammation, University of Leicester

Redefining the mechanism of action of D-cycloserine in Mycobacterium tuberculosis
Gareth A. Prosser, Luiz Pedro Carvalho, National Institute for Medical Research, The Ridgeway, Mill Hill, London

AZALEP A randomized controlled trial of azathioprine to treat leprosy nerve damage and reactions in India: main findings
Lockwood DNJ, Darlong J, Pichimani G, Royce KK, Sundar Rao, Annamma John, London School of Hygiene & Tropical Medicine, London

A guide to killing your host cell, by Mycobacterium tuberculosis
Graham Stewart, Robert Francis, Rachel Butler, Tom Mendum, Shaza Felemban, University of Surrey

Meeting programme details Word file