AFC Winter meeting 2025
10th January 2025
Programme of speakers, associates, affiliations and presented titles
(Speakers indicated in Bold)
Welcome by AFC Chair, Mike Barer
Session 1: Host session
Screening for viable Mycobacterium avium subspecies paratuberculosis in human PBMC fractions reveals high rate of carriage in both normal and disease cohorts.
Tim Bull, Bina Makwana, Metin Yalcin, Dan Forton, Todd Kuenstner, Saleh Naser, Irene Grant.
City St George’s University of London
_______________________________________
The tricarboxylic acid cycle (TCA) regulates fibroblast-driven tissue remodelling during Mycobacterium tuberculosis infection.
Ramla Cusman, Julia Kutschenreuter, Deborah LW Chong, Jon S Friedland.
City St George’s University of London
_______________________________________
Targeting neutrophil extracellular traps (NETs) prevents TB immunopathology.
Julia Kutschenreuter, Daniela E Kirwan, Ramla Cusman, Keira H Skolimowska, Jon S Friedland, Deborah
LW Chong.
City St George’s University of London
_______________________________________
Serological analysis reveals differential antibody responses between TB patients and latently infected individuals from the TB endemic country of Mozambique.
Andy C. Tran, Matthew J. Paul, Eugenia Boariu, María García-Bengoa, MiYoung Kim, Emil Joseph Vergara, Tufária Mussá, Rajko Reljic.
City St George’s University of London
_______________________________________
Session 2: Selected papers from submitted abstracts
Development of a phage-based molecular assay to detect human Mycobacterium tuberculosis infection in blood.
Maeve Woodhouse, Galina Mukamolova, Pranabashis Haldar, Jo Lee, Ismail Novsarka, Kim Jee-Whang, Benjamin Swift, Catherine Rees.
University of Leicester
_______________________________________
Mycobacterium tuberculosis-phagosome Ca2+ leakage triggers multimembrane ATG8/LC3 lipidation to restrict damage in human macrophages.
Di Chen, Antony Fearns and Maximiliano Gutierrez.
The Francis Crick Institute.
_______________________________________
Session 3: Selected papers from submitted abstracts
Studying antimicrobial resistance using computational approaches
Arun Prasad Pandurangan.
University of Cambridge
_______________________________________
CD1c-autoreactive T-cells exhibit potent responses to Mycobacterium tuberculosis.
Matthew Milton, Sahar H Faraga, Jennie Gullicka,Diana Garay-Baqueroa, Daniel Burnsa, Rita Szoke-Kovacsc, Patrick Trimby-Smitha, Alex Looka, Richard Stopfortha, Marco Leporec, David K Colec, Laura Denney, Andrew White, Sally Sharpe, Alasdair Leslied, Liku Tezera, Paul Elkington, Salah Mansoura.
University of Southampton
_______________________________________
Making ‘antisense’ of the PhoPR two-component system in the Mycobacterium tuberculosis complex.
Jennifer Stiens, Irilenia Nobeli, Sharon Kendall.
Birbeck University of London.
_______________________________________
Assessment of the Riboflavin Biosynthesis Pathway as a Potential Target for Tuberculosis Treatment.
Enkai Jin, Dimitrios Evangelopoulos.
Eastman Dental Institute, University College London.
_______________________________________
Protective Efficacy of a Novel Protein Adjuvanted Formulation PPE15- LMQ: A Promising Tuberculosis Vaccine Candidate.
Marcellus Korompis, Christopher De Voss, Shuailin Li, Alexandre Richard, Salem
Almujri, Géraldine Frank, Céline Lemoine, Helen McShane, and Elena
Stylianou.
The Jenner Institute, University of Oxford.