BRUNEL UNIVERSITY

AFC Winter meeting 2024

5th January 2024

Programme of speakers, associates, affiliations and presented titles

(Speakers indicated in Bold)

Welcome by AFC Chair, Tim McHugh

Session 1: Host session

Introduction from the host institute.

Paul Hellewell. Head of the College of Health, Medicine and Life Sciences,

Brunel University London.

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A novel PE/PPE protein subfamily of Mycobacterium tuberculosis.

Christopher D’Souza, Paula-Josefina Gomez-Gonzalez, Taane Clark, Jody Phelan, Anthony G. Tsolaki.

Brunel University London.

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Drug Repurposing in Tuberculosis: An Untapped Potential for Treatment.

Sam Willcocks.

Brunel University London.

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Session 2: Selected papers from submitted abstracts

T cell compromise of Mycobacterium tuberculosis (Mtb) restriction by macrophages.

Clare Thacker, Aneesh Chandran, Matthew V.X. Whelan, Mahdad Noursadeghi.

University College London.

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Metabolites tune the antimicrobial susceptibility of Mycobacterium tuberculosis.

Jordan Pascoe, Mark Laws, Jane Newcombe, Claudio Avignone Rossa, Miraz Rahman, Dany J. V. Beste.

University of Surrey.

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A whole genome sequencing pipeline for Mycobacterium tuberculosis using Oxford Nanopore Technologies for use in resource constrained settings.

Linzy Elton, Neil Stoker, Sylvia Rofael, Letícia Muraro Wildner, Jabar Babatunde Pacome Agbo Achimi Abdul, John Tembo, Julio Ortiz Canseco, Ronan Doyle, Giovanni Satta, Adam Whitney, Timothy D. McHugh.

University College London.

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Session 3 : Selected papers from submitted abstracts

Integrated plasma proteomics identified tuberculosis-specific diagnostic biomarkers.

Hannah Schiff, Naomi F. Walker, Cesar Ugarte-Gil, Marc Tebruegge, Antigoni Manousopoulou, Spiros D. Gabris, Salah Mansour, Mahesan Niranjan, Andres F. Vallejo, Christopher H. Woelk, Robert J. Wilkinson, Liku B. Tezera, Diana Garay-Baquero, Paul Elkington.

University of Southampton.

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The effect of drug presence and growth phase on different bacterial load determination methodologies.

Frank Kloprogge, Arundhati Maitra, Marie Wijk, Hasmik Margaryan, Paolo Denti, Timothy McHugh.

University College London.

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Development of new serological tools for the identification of vaccinated and infected badgers for the control of bovine tuberculosis.

Dipesh Dave, Sabah Rahou, Oliver Bateman, Shelley Rhodes, Martin Vordermeier, Philip J. Hogarth, Jason Sawyer, Richard Delahay, Laura Arnold, Angela Yee, Joe Campo, Andy Teng.

Animal and Plant Health Agency.

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Innovation in developing anti-TB antibiotics in the age of antimicrobial resistance.

Mark Laws, Jennifer Auer, Taha Al-Adhami, Chris Moon, Adam Roberts, Joanna Bacon, Jordan Pascoe, Jane Newcombe, Dany Beste and Miraz Rahman.

King’s College London.

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Lessons for TB treatment from the zebrafish.

Lalita Ramakrishnan.

University of Cambridge.

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